DBR Publications


Stretchable multichannel antennas in soft wireless optoelectronic implants for optogenetics.

Park SI, Shin G, McCall JG, Al-Hasani R, Norris A, Xia L, Brenner DS, Noh KN, Bang SY, Bhatti DL, Jang KI, Kang SK, Mickle AD, Dussor G, Price TJ, Gereau RW 4th, Bruchas MR, Rogers JA. (2016) Stretchable multichannel antennas in soft wireless optoelectronic implants for optogenetics. Proceedings of the National Academy of Sciences of the United States of America, 113(50):E8169-E8177.

Gereau Lab Bruchas Lab  PubMed


A Trigger for Opioid Misuse: Chronic Pain and Stress Dysregulate the Mesolimbic Pathway and Kappa Opioid System.

Massaly N, Morón JA, Al-Hasani R (2016) A Trigger for Opioid Misuse: Chronic Pain and Stress Dysregulate the Mesolimbic Pathway and Kappa Opioid System. Frontiers in neuroscience, 10():480.

Moron-Concepcion Lab  PubMed


Identification of an epidermal keratinocyte AMPA glutamate receptor involved in dermatopathies associated with sensory abnormalities

Cabanero D, Irie T, Celorrio M, Trousdale C, Owens DM, Virley D, Albrecht PH, Caterina MJ, Rice FL, Moron JA (2016) Identification of an epidermal keratinocyte AMPA glutamate receptor involved in dermatopathies associated with sensory abnormalities PAIN Reports, ():.

Moron-Concepcion Lab  PubMed


Frontline Science: Defects in immune function in patients with sepsis are associated with PD-1 or PD-L1 expression and can be restored by antibodies targeting PD-1 or PD-L1.

Patera AC, Drewry AM, Chang K, Beiter ER, Osborne D, Hotchkiss RS (2016) Frontline Science: Defects in immune function in patients with sepsis are associated with PD-1 or PD-L1 expression and can be restored by antibodies targeting PD-1 or PD-L1. Journal of leukocyte biology, ():.

Hotchkiss Lab  PubMed


Stress-Induced Reinstatement of Nicotine Preference Requires Dynorphin/Kappa Opioid Activity in the Basolateral Amygdala.

Nygard SK, Hourguettes NJ, Sobczak GG, Carlezon WA, Bruchas MR (2016) Stress-Induced Reinstatement of Nicotine Preference Requires Dynorphin/Kappa Opioid Activity in the Basolateral Amygdala. The Journal of neuroscience : the official journal of the Society for Neuroscience, 36(38):9937-48.

Bruchas Lab  PubMed


PEGylated Artificial Antibodies: Plasmonic Biosensors with Improved Selectivity.

Luan J, Liu KK, Tadepalli S, Jiang Q, Morrissey JJ, Kharasch ED, Singamaneni S (2016) PEGylated Artificial Antibodies: Plasmonic Biosensors with Improved Selectivity. ACS applied materials & interfaces, 8(36):23509-16.

Kharasch Lab  PubMed


Interleukin 7 immunotherapy improves host immunity and survival in a two-hit model of Pseudomonas aeruginosa pneumonia.

Shindo Y, Fuchs AG, Davis CG, Eitas T, Unsinger J, Burnham CD, Green JM, Morre M, Bochicchio GV, Hotchkiss RS (2016) Interleukin 7 immunotherapy improves host immunity and survival in a two-hit model of Pseudomonas aeruginosa pneumonia. Journal of leukocyte biology, ():.

Hotchkiss Lab  PubMed


Surgical extraction of human dorsal root ganglia from organ donors and preparation of primary sensory neuron cultures.

Valtcheva MV, Copits BA, Davidson S, Sheahan TD, Pullen MY, McCall JG, Dikranian K, Gereau RW 4th (2016) Surgical extraction of human dorsal root ganglia from organ donors and preparation of primary sensory neuron cultures. Nature Protocols, 11(10):1877-88.

Gereau Lab  PubMed


Synthesis and Characteristics of FePt Nanoparticle Films Under In Situ-Applied Magnetic Field.

Qian X, Gao MY, Li AD, Zhou XY, Liu XJ, Cao YQ, Li C, Wu D (2016) Synthesis and Characteristics of FePt Nanoparticle Films Under In Situ-Applied Magnetic Field. Nanoscale research letters, 11(1):325.

Cao Lab  PubMed


Pharmacokinetics and analgesic effects of methadone in children and adults with sickle cell disease.

Horst J, Frei-Jones M, Deych E, Shannon W, Kharasch ED (2016) Pharmacokinetics and analgesic effects of methadone in children and adults with sickle cell disease. Pediatric blood & cancer, ():.

Kharasch Lab  PubMed


Silk-Encapsulated Plasmonic Biochips with Enhanced Thermal Stability.

Wang C, Luan J, Tadepalli S, Liu KK, Morrissey JJ, Kharasch ED, Naik RR, Singamaneni S (2016) Silk-Encapsulated Plasmonic Biochips with Enhanced Thermal Stability. ACS applied materials & interfaces, ():.

Kharasch Lab  PubMed


CASE 8-2016 Percutaneous Fetal Cardiac Intervention for Severe Aortic Stenosis and Evolving Hypoplastic Left-Heart Syndrome.

Ferschl MB, Moon-Grady AJ, Rollins MD, Gilliss B, Schulman SR, Tulzer G, Stohl S, Ginosar Y (2016) CASE 8-2016 Percutaneous Fetal Cardiac Intervention for Severe Aortic Stenosis and Evolving Hypoplastic Left-Heart Syndrome. Journal of cardiothoracic and vascular anesthesia, 30(4):1118-28.

Ginosar Lab  PubMed


In Reply.

Avidan MS, Evers AS (2016) In Reply. Anesthesiology, 125(2):428-9.

Evers Lab  PubMed


Development, validation and application of a comprehensive stereoselective LC/MS-MS assay for bupropion and oxidative, reductive, and glucuronide metabolites in human urine.

Teitelbaum AM, Flaker AM, Kharasch ED (2016) Development, validation and application of a comprehensive stereoselective LC/MS-MS assay for bupropion and oxidative, reductive, and glucuronide metabolites in human urine. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1027():239-53.

Kharasch Lab  PubMed


Activation and modulation of recombinant glycine and GABAA receptors by 4-halogenated analogues of propofol.

Germann AL, Shin DJ, Manion BD, Edge CJ, Smith EH, Franks NP, Evers AS, Akk G (2016) Activation and modulation of recombinant glycine and GABAA receptors by 4-halogenated analogues of propofol. British journal of pharmacology, 173(21):3110-3120.

Akk Lab Evers Lab  PubMed


Chemogenetic and Optogenetic Activation of Gαs Signaling in the Basolateral Amygdala Induces Acute and Social Anxiety-Like States.

Siuda ER, Al-Hasani R, McCall JG, Bhatti DL, Bruchas MR (2016) Chemogenetic and Optogenetic Activation of Gαs Signaling in the Basolateral Amygdala Induces Acute and Social Anxiety-Like States. Neuropsychopharmacology: official publication of the American College of Neuropsychopharmacology, 41(8):2011-23.

Bruchas Lab  PubMed


Changes: Thank You, Dr. Eisenach.

Kharasch ED, Tedeschi V, Kendall G (2016) Changes: Thank You, Dr. Eisenach. Anesthesiology, 125(1):1-3.

Kharasch Lab  PubMed


Changes: Handing Off and the Future of ANESTHESIOLOGY.

Kharasch ED (2016) Changes: Handing Off and the Future of ANESTHESIOLOGY. Anesthesiology, 125(1):4-6.

Kharasch Lab  PubMed


Synthetic Ligands of Cannabinoid Receptors Affect Dauer Formation in the Nematode Caenorhabditis elegans.

Reis Rodrigues P, Kaul TK, Ho JH, Lucanic M, Burkewitz K, Mair WB, Held JM, Bohn LM, Gill MS (2016) Synthetic Ligands of Cannabinoid Receptors Affect Dauer Formation in the Nematode Caenorhabditis elegans. G3 (Bethesda, Md.), 6(6):1695-705.

Held Lab  PubMed


Architectural Representation of Valence in the Limbic System.

Namburi P, Al-Hasani R, Calhoon GG, Bruchas MR, Tye KM (2016) Architectural Representation of Valence in the Limbic System. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 41(7):1697-715.

Bruchas Lab  PubMed


Is this critically ill patient immunocompromised?

Pène F, Pickkers P, Hotchkiss RS (2016) Is this critically ill patient immunocompromised? Intensive care medicine, 42(6):1051-4.

Hotchkiss Lab  PubMed


Erratum to: Is this critically ill patient immunocompromised?

Pène F, Pickkers P, Hotchkiss RS (2016) Erratum to: Is this critically ill patient immunocompromised? Intensive care medicine, 42(6):1106.

Hotchkiss Lab  PubMed


Group II mGluRs suppress hyperexcitability in mouse and human nociceptors.

Davidson S, Golden JP, Copits BA, Ray PR, Vogt SK, Valtcheva MV, Schmidt RE, Ghetti A, Price T, Gereau RW 4th (2016) Group II mGluRs suppress hyperexcitability in mouse and human nociceptors. Pain, 157(9):2081-8.

Gereau Lab  PubMed


Spotlight on pain: optogenetic approaches for interrogating somatosensory circuits.

Copits BA, Pullen MY, Gereau RW 4th (2016) Spotlight on pain: optogenetic approaches for interrogating somatosensory circuits. Pain, 157(11):2424-2433..

Gereau Lab  PubMed


Morphine-Associated Contextual Cues Induce Structural Plasticity in Hippocampal CA1 Pyramidal Neurons.

Fakira AK, Massaly N, Cohensedgh O, Berman A, Morón JA (2016) Morphine-Associated Contextual Cues Induce Structural Plasticity in Hippocampal CA1 Pyramidal Neurons. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, ():.

Moron-Concepcion Lab  PubMed


The Complement System Component C5a Produces Thermal Hyperalgesia via Macrophage-to-Nociceptor Signaling That Requires NGF and TRPV1.

Shutov LP, Warwick CA, Shi X, Gnanasekaran A, Shepherd AJ, Mohapatra DP, Woodruff TM, Clark JD, Usachev YM (2016) The Complement System Component C5a Produces Thermal Hyperalgesia via Macrophage-to-Nociceptor Signaling That Requires NGF and TRPV1. The Journal of neuroscience : the official journal of the Society for Neuroscience, 36(18):5055-70.

Mohapatra Lab  PubMed


A Novel Proliposomal Ropivacaine Oil: Pharmacokinetic-Pharmacodynamic Studies After Subcutaneous Administration in Pigs.

Davidson EM, Haroutounian S, Kagan L, Naveh M, Aharon A, Ginosar Y (2016) A Novel Proliposomal Ropivacaine Oil: Pharmacokinetic-Pharmacodynamic Studies After Subcutaneous Administration in Pigs. Anesthesia and analgesia, 122(5):1663-72.

Ginosar Lab  PubMed


Proliposomal Ropivacaine Oil: Pharmacokinetic and Pharmacodynamic Data After Subcutaneous Administration in Volunteers.

Ginosar Y, Haroutounian S, Kagan L, Naveh M, Aharon A, Davidson EM (2016) Proliposomal Ropivacaine Oil: Pharmacokinetic and Pharmacodynamic Data After Subcutaneous Administration in Volunteers. Anesthesia and analgesia, 122(5):1673-80.

Ginosar Lab  PubMed


Gestational sleep apnea: have we been caught napping?

Karan S, Ginosar Y (2016) Gestational sleep apnea: have we been caught napping? International journal of obstetric anesthesia, 26():1-3.

Ginosar Lab  PubMed


The GAS trial.

Orser BA, Evers AS, Suresh S, Hertz S (2016) The GAS trial. Lancet (London, England), 387(10028):1613-4.

Evers Lab  PubMed


Lung-protective ventilation initiated in the emergency department (LOV-ED): a study protocol for a quasi-experimental, before-after trial aimed at reducing pulmonary complications.

Fuller BM, Ferguson I, Mohr NM, Stephens RJ, Briscoe CC, Kolomiets AA, Hotchkiss RS, Kollef MH (2016) Lung-protective ventilation initiated in the emergency department (LOV-ED): a study protocol for a quasi-experimental, before-after trial aimed at reducing pulmonary complications. BMJ open, 6(4):e010991.

Hotchkiss Lab  PubMed


Characterization of a mouse model of headache.

Huang D, Ren L, Qiu CS, Liu P, Peterson J, Yanagawa Y, Cao YQ (2016) Characterization of a mouse model of headache. Pain, ():.

Cao Lab  PubMed


New Technologies for Elucidating Opioid Receptor Function.

Bruchas MR, Roth BL (2016) New Technologies for Elucidating Opioid Receptor Function. Trends in pharmacological sciences, 37(4):279-89.

Bruchas Lab  PubMed


Understanding why clinicians should care about danger-associated molecular patterns.

Asehnoune K, Hotchkiss RS, Monneret G (2016) Understanding why clinicians should care about danger-associated molecular patterns. Intensive care medicine, 42(4):611-4.

Hotchkiss Lab  PubMed


Fentanyl and Midazolam Are Ineffective in Reducing Episodic Intracranial Hypertension in Severe Pediatric Traumatic Brain Injury.

Welch TP, Wallendorf MJ, Kharasch ED, Leonard JR, Doctor A, Pineda JA (2016) Fentanyl and Midazolam Are Ineffective in Reducing Episodic Intracranial Hypertension in Severe Pediatric Traumatic Brain Injury. Critical care medicine, 44(4):809-18.

Kharasch Lab  PubMed


Perioperative Opioids and Public Health.

Kharasch ED, Brunt LM (2016) Perioperative Opioids and Public Health. Anesthesiology, 124(4):960-5.

Kharasch Lab  PubMed


Development and validation of a high-throughput stereoselective LC-MS/MS assay for bupropion, hydroxybupropion, erythrohydrobupropion, and threohydrobupropion in human plasma.

Teitelbaum AM, Flaker AM, Kharasch ED (2016) Development and validation of a high-throughput stereoselective LC-MS/MS assay for bupropion, hydroxybupropion, erythrohydrobupropion, and threohydrobupropion in human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1017-1018():101-13.

Kharasch Lab  PubMed


Dynorphin Controls the Gain of an Amygdalar Anxiety Circuit.

Crowley NA, Bloodgood DW, Hardaway JA, Kendra AM, McCall JG, Al-Hasani R, McCall NM, Yu W, Schools ZL, Krashes MJ (2016) Dynorphin Controls the Gain of an Amygdalar Anxiety Circuit. Cell reports, 14(12):2774-83.

Bruchas Lab  PubMed


Subcellular optogenetic activation of Cdc42 controls local and distal signaling to drive immune cell migration.

O'Neill PR, Kalyanaraman V, Gautam N (2016) Subcellular optogenetic activation of Cdc42 controls local and distal signaling to drive immune cell migration. Molecular biology of the cell, ():E15-12-0832. [Epub ahead of print].

Gautam Lab  PubMed


The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).

Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, Bellomo R, Bernard GR, Chiche JD, Coopersmith CM, Hotchkiss RS, Levy MM, Marshall JC, Martin GS, Opal SM, Rubenfeld GD, van der Poll T, Vincent JL, Angus DC (2016) The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA, 315(8):801-10.

Hotchkiss Lab  PubMed


The Effect of Medicinal Cannabis on Pain and Quality of Life Outcomes in Chronic Pain: A Prospective Open-label Study.

Haroutounian S, Ratz Y, Ginosar Y, Furmanov K, Saifi F, Meidan R, Davidson E (2016) The Effect of Medicinal Cannabis on Pain and Quality of Life Outcomes in Chronic Pain: A Prospective Open-label Study. The Clinical journal of pain, ():.

Ginosar Lab  PubMed


Multiple Non-Equivalent Interfaces Mediate Direct Activation of GABAA Receptors by Propofol.

Eaton MM, Germann AL, Arora R, Cao LQ, Gao X, Shin DJ, Wu A, Chiara DC, Cohen JB, Steinbach JH (2016) Multiple Non-Equivalent Interfaces Mediate Direct Activation of GABAA Receptors by Propofol. Current neuropharmacology, 14(7):772-780.

Akk Lab Evers Lab  PubMed


Convergent phosphomodulation of the major neuronal dendritic potassium channel Kv4.2 by pituitary adenylate cyclase-activating polypeptide.

Gupte RP, Kadunganattil S, Shepherd AJ, Merrill R, Planer W, Bruchas MR, Strack S, Mohapatra DP (2016) Convergent phosphomodulation of the major neuronal dendritic potassium channel Kv4.2 by pituitary adenylate cyclase-activating polypeptide. Neuropharmacology, 101():291-308.

Bruchas Lab Mohapatra Lab  PubMed


The Fallacy of Persistent Postoperative Cognitive Decline.

Avidan MS, Evers AS (2016) The Fallacy of Persistent Postoperative Cognitive Decline. Anesthesiology, 124(2):255-8.

Evers Lab  PubMed


T cells from patients with Candida sepsis display a suppressive immunophenotype.

Spec A, Shindo Y, Burnham CA, Wilson S, Ablordeppey EA, Beiter ER, Chang K, Drewry AM, Hotchkiss RS (2016) T cells from patients with Candida sepsis display a suppressive immunophenotype. Critical care (London, England), 20():15.

Hotchkiss Lab  PubMed


Comparison of Steroid Modulation of Spontaneous Inhibitory Postsynaptic Currents in Cultured Hippocampal Neurons and Steady-State Single-Channel Currents from Heterologously Expressed α1β2γ2L GABAA Receptors.

Chakrabarti S, Qian M, Krishnan K, Covey DF, Mennerick S, Akk G (2016) Comparison of Steroid Modulation of Spontaneous Inhibitory Postsynaptic Currents in Cultured Hippocampal Neurons and Steady-State Single-Channel Currents from Heterologously Expressed α1β2γ2L GABAA Receptors. Molecular pharmacology, 89(4):399-406.

Akk Lab  PubMed


Allosteric signaling through an mGlu2 and 5-HT2A heteromeric receptor complex and its potential contribution to schizophrenia.

Moreno JL, Miranda-Azpiazu P, García-Bea A, Younkin J, Cui M, Kozlenkov A, Ben-Ezra A, Voloudakis G, Fakira AK, Baki L, Ge Y, Georgakopoulos A, Morón JA, Milligan G, López-Giménez JF, Robakis NK, Logothetis DE, Meana JJ, González-Maeso J. (2016) Allosteric signaling through an mGlu2 and 5-HT2A heteromeric receptor complex and its potential contribution to schizophrenia. Science signaling, 9(410):ra5.

Moron-Concepcion Lab  PubMed


Surgeon-Performed Hemodynamic Transesophageal Echocardiography in the Burn Intensive Care Unit.

Held JM, Litt J, Kennedy JD, McGrane S, Gunter OL, Rae L, Kahn SA (2016) Surgeon-Performed Hemodynamic Transesophageal Echocardiography in the Burn Intensive Care Unit. Journal of burn care & research : official publication of the American Burn Association, 37(1):e63-8.

Held Lab  PubMed


Wherefore Gabapentinoids?: Was There Rush Too Soon to Judgment?

Kharasch ED, Eisenach JC (2016) Wherefore Gabapentinoids?: Was There Rush Too Soon to Judgment? Anesthesiology, 124(1):10-2.

Kharasch Lab  PubMed


Introduced Amino Terminal Epitopes Can Reduce Surface Expression of Neuronal Nicotinic Receptors.

Bracamontes JR, Akk G, Steinbach JH (2016) Introduced Amino Terminal Epitopes Can Reduce Surface Expression of Neuronal Nicotinic Receptors. PloS one, 11(3):e0151071.

Akk Lab  PubMed