1. This course provides a heuristic, semi-quantitative and integrative approach to concepts in somatosensory biology, primarily focusing on pain and itch. Relevant principles and quantitative methods are reviewed to facilitate the application of abstract concepts to the mechanistic understanding of pain, touch and itch processing, based on extensive research literature and observations in rodents and humans. Clinical pain and itch syndromes in humans, as well as investigative rodent models pain and itch are presented and discussed in the context of cellular/neurophysiological mechanisms. This course also also discusses the mechanisms of action of analgesics at molecular, cellular and organism levels, and provide a review of recent advances in the discovery and development of new-generation analgesics. Student/trainee presentations and group discussions are incorporated at regular intervals between the lecture line-up for discussion of recent research findings on those relevant topics/areas. The overall goal of this course is to develop in-depth understanding of somatosensory biology, specifically underlying the processing of pain and itch, which would ultimately empower the students and trainees with knowledge and expertise in these areas of Anesthesiology and Neurobiology.

  2. Course Number:  [In Process]

  3. Student Trainee Groups:

  4. BulletResidents and Clinical Fellows in Anesthesiology

  5. BulletMSTP & Graduate Students in Biological and Biomedical Sciences with focus on Neuroscience

  6. BulletGraduate Students in Physical Therapy and Rehabilitation Science

  7. BulletUndergraduate Biology Student with Neurobiology Major

  8. Semester and Course Credit:  Spring Semester; 3 semester hours

  9. Course Schedule:  05:00 PM to 06:30 PM; Mondays and Wednesdays

  10. Lecture Venue:  5550 Clinical Science Research Building (CSRB)

  11. Course Directors (or Coursemasters):      Dr. D.P. Mohapatra (Primary)

  12.                                                                   Associate Professor of Anesthesiology

  13.                                                                   Department of Anesthesiology, Washington University Pain Center

  14.                                                                   Washington University School of Medicine in St. Louis

  15.                                                                   5502 CSRB, Tel. (314) 362 8229

  16.                                                                   email: mohapatrad@anest.wustl.edu


  18.                                                                   Dr. Robert W. Gereau IV (Secondary)

  19.                                                                   Dr. Seymour and Rose T. Brown Professor of Anesthesiology

  20.                                                                   Chief, Division of Basic Research, Department of Anesthesiology

  21.                                                                   Director, Washington University Pain Center

  22.                                                                   Washington University School of Medicine in St. Louis

  23.                                                                   5502 CSRB, Tel. (314) 362 8312

  24.                                                                   email: gereaur@wustl.edu

  25.                                                                   Dr. Lesley K. Rao (Secondary)

  26.                                                                   Assistant Professor of Anesthesiology

  27.                                                                   Division of Pain Management, Department of Anesthesiology

  28.                                                                   Washington University Pain Center

  29.                                                                   Washington University School of Medicine in St. Louis

  30.                                                                   C-14, 4921 Parkview Pl, Tel. (314) 362 8820

  31.                                                                   email: raol@anest.wustl.edu

        Our Contact Address:

        Washington University Pain Center       

        Department of Anesthesiology, 5502 CSRB

        Washington University School of Medicine in St. Louis

        660 S. Euclid Avenue, St. Louis, MO, 63110

        Voice:  (314) 362 8229; FAX:  (314) 362 8334