Interleukin-7 (IL-7) treatment accelerates neutrophil recruitment through gamma delta T-cell IL-17 production in a murine model of sepsis.

Kasten K.R., Prakash P.S., Unsinger J., Goetzman H.S., England L.G., Cave C.M., Seitz A.P., Mazuski C.N., Zhou T.T., Morre M., Hotchkiss R.S., Hildeman D.A., Caldwell C.C. (2010) Interleukin-7 (IL-7) treatment accelerates neutrophil recruitment through gamma delta T-cell IL-17 production in a murine model of sepsis. Infection and immunity, 78(11):4714-22.

 PubMed


Clinical microfluidics for neutrophil genomics and proteomics.

Kotz K.T., Xiao W., Miller-Graziano C., Qian W.-J., Russom A., Warner E.A., Moldawer L.L., De A., Bankey P.E., Petritis B.O., Camp II D.G., Rosenbach A.E., Goverman J., Fagan S.P., Brownstein B.H., Irimia D., Xu W., Wilhelmy J., Mindrinos M.N., Smith R.D., Davis R.W., Tompkins R.G., Toner M. (2010) Clinical microfluidics for neutrophil genomics and proteomics. Nature medicine, 16(9):1042-7.

 PubMed


Immunotherapy for sepsis--a new approach against an ancient foe.

Hotchkiss R.S., Opal S. (2010) Immunotherapy for sepsis--a new approach against an ancient foe. The New England journal of medicine, 363(1):87-9.

 PubMed


A genetically encoded multifunctional TRAIL trimer facilitates cell-specific targeting and tumor cell killing.

Spitzer D., McDunn J.E., Plambeck-Suess S., Goedegebuure P.S., Hotchkiss R.S., Hawkins W.G. (2010) A genetically encoded multifunctional TRAIL trimer facilitates cell-specific targeting and tumor cell killing. Molecular cancer therapeutics, 9(7):2142-51.

 PubMed


IL-7 promotes T cell viability, trafficking, and functionality and improves survival in sepsis.

Unsinger J., McGlynn M., Kasten K.R., Hoekzema A.S., Watanabe E., Muenzer J.T., McDonough J.S., Tschoep J., Ferguson T.A., McDunn J.E., Morre M., Hildeman D.A., Caldwell C.C., Hotchkiss R.S. (2010) IL-7 promotes T cell viability, trafficking, and functionality and improves survival in sepsis. Journal of immunology (Baltimore, Md. : 1950), 184(7):3768-79.

 PubMed


Characterization and modulation of the immunosuppressive phase of sepsis.

Muenzer J.T., Davis C.G., Chang K., Schmidt R.E., Dunne W.M., Coopersmith C.M., Hotchkiss R.S. (2010) Characterization and modulation of the immunosuppressive phase of sepsis. Infection and immunity, 78(4):1582-92.

 PubMed


Cancer causes increased mortality and is associated with altered apoptosis in murine sepsis.

Fox A.C., Robertson C.M., Belt B., Clark A.T., Chang K.C., Leathersich A.M., Dominguez J.A., Perrone E.E., Dunne W.M., Hotchkiss R.S., Buchman T.G., Linehan D.C., Coopersmith C.M. (2010) Cancer causes increased mortality and is associated with altered apoptosis in murine sepsis. Critical care medicine, 38(3):886-93.

 PubMed


Bim-Bcl-2 homology 3 mimetic therapy is effective at suppressing inflammatory arthritis through the activation of myeloid cell apoptosis.

Scatizzi J.C., Hutcheson J., Pope R.M., Firestein G.S., Koch A.E., Mavers M., Smason A., Agrawal H., Haines III G.K., Chandel N.S., Hotchkiss R.S., Perlman H. (2010) Bim-Bcl-2 homology 3 mimetic therapy is effective at suppressing inflammatory arthritis through the activation of myeloid cell apoptosis. Arthritis and rheumatism, 62(2):441-51.

 PubMed


Mechanisms and consequences of ebolavirus-induced lymphocyte apoptosis.

Bradfute S.B., Swanson P.E., Smith M.A., Watanabe E., McDunn J.E., Hotchkiss R.S., Bavari S. (2010) Mechanisms and consequences of ebolavirus-induced lymphocyte apoptosis. Journal of immunology (Baltimore, Md. : 1950), 184(1):327-35.

 PubMed