Neutrophil depletion causes a fatal defect in murine pulmonary Staphylococcus aureus clearance.

Robertson C.M., Perrone E.E., McConnell K.W., Dunne W.M., Boody B., Brahmbhatt T., Diacovo M.J., Van Rooijen N., Hogue L.A., Cannon C.L., Buchman T.G., Hotchkiss R.S., Coopersmith C.M. (2008) Neutrophil depletion causes a fatal defect in murine pulmonary Staphylococcus aureus clearance. The Journal of surgical research, 150(2):278-85.

 PubMed


Microfluidic leukocyte isolation for gene expression analysis in critically ill hospitalized patients.

Russom A., Sethu P., Irimia D., Mindrinos M.N., Calvano S.E., Garcia I., Finnerty C., Tannahill C., Abouhamze A., Wilhelmy J., Lopez M.C., Baker H.V., Herndon D.N., Lowry S.F., Maier R.V., Davis R.W., Moldawer L.L., Tompkins R.G., Toner M., Bankey P.E., Billiar T.R., Brownstein B.H., Camp II D.G., Casella G., Chaudry I.H., Choudhry M., Cobb J.P., De A., Elson C., Freeman B., Gamelli R.L., Gibran N.S., Hayden D.L., Harbrecht B.G., Horton J.W., Hubbard W., Johnson J., Klein M.B., Lederer J.A., Logvinenko T., Mannick J.A., Mason P.H., McDonald-Smith G.P., McKinley B.A., Miller-Graziano C., Minei J.P., Moore E.E., Moore F.A., Nathens A.B., O'Keefe G.E., Rahme L.G., Remick D.G., Schoenfeld D.A., Shapiro M.B., Schwacha M., Silver G.M., Smith R.D., Storey J., Warren H.S., West M.A., Xiao W. (2008) Microfluidic leukocyte isolation for gene expression analysis in critically ill hospitalized patients. Clinical chemistry, 54(5):891-900.

 PubMed


Deletion of MyD88 markedly attenuates sepsis-induced T and B lymphocyte apoptosis but worsens survival.

Peck-Palmer O.M., Unsinger J., Chang K.C., Davis C.G., McDunn J.E., Hotchkiss R.S. (2008) Deletion of MyD88 markedly attenuates sepsis-induced T and B lymphocyte apoptosis but worsens survival. Journal of leukocyte biology, 83(4):1009-18.

 PubMed


Intestine-specific overexpression of IL-10 improves survival in polymicrobial sepsis.

Rajan S., Vyas D., Clark A.T., Woolsey C.A., Clark J.A., Hotchkiss R.S., Buchman T.G., Coopersmith C.M. (2008) Intestine-specific overexpression of IL-10 improves survival in polymicrobial sepsis. Shock (Augusta, Ga.), 29(4):483-9.

 PubMed


Comparison of longitudinal leukocyte gene expression after burn injury or trauma-hemorrhage in mice.

Lederer J.A., Brownstein B.H., Lopez M.C., MacMillan S., Delisle A.J., MacConmara M.P., Choudhry M.A., Xiao W., Lekousi S., Cobb J.P., Baker H.V., Mannick J.A., Chaudry I.H., Balis U., Bankey P., Billiar T.R., Calvano S.E., Camp II D.G., Cuschieri J., Davis R.W., De A.K., Elson C., Finnerty C.C., Freeman B., Gamelli R.L., Gibran N.S., Harbrecht B.G., Hayden D.L., Hennessy L., Herndon D.N., Horton J.W., Jeschke M.G., Johnson J., Klein M.B., Lowry S.F., Maier R.V., Mason P.H., McDonald-Smith G.P., Miller-Graziano C.L., Mindrinos M.N., Minei J.P., Moldawer L.L., Moore E.E., Nathens A.B., O'Keefe G.E., Rahme L.G., Remick Jr. D.G., Schoenfeld D.A., Shapiro M.B., Silver G.M., Smith R.D., Storey J., Tibshirani R., Tompkins R.G., Toner M., Warren H.S., West M.A. (2008) Comparison of longitudinal leukocyte gene expression after burn injury or trauma-hemorrhage in mice. Physiological genomics, 32(3):299-310.

 PubMed


Lymphocyte phenotyping to distinguish septic from nonseptic critical illness.

Schwulst S.J., Muenzer J.T., Chang K.C., Brahmbhatt T.S., Coopersmith C.M., Hotchkiss R.S. (2008) Lymphocyte phenotyping to distinguish septic from nonseptic critical illness. Journal of the American College of Surgeons, 206(2):335-42.

 PubMed


Peptide-mediated activation of Akt and extracellular regulated kinase signaling prevents lymphocyte apoptosis.

McDunn J.E., Muenzer J.T., Rachdi L., Chang K.C., Davis C.G., Dunne W.M., Piwnica-Worms D., Bernal-Mizrachi E., Hotchkiss R.S. (2008) Peptide-mediated activation of Akt and extracellular regulated kinase signaling prevents lymphocyte apoptosis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 22(2):561-8.

 PubMed