The metabotropic glutamate receptor subtype 5 antagonist fenobam is analgesic and has improved in vivo selectivity compared with the prototypical antagonist 2-methyl-6-(phenylethynyl)-pyridine.

Montana M.C., Cavallone L.F., Stubbert K.K., Stefanescu A.D., Kharasch E.D., Gereau IV R.W. (2009) The metabotropic glutamate receptor subtype 5 antagonist fenobam is analgesic and has improved in vivo selectivity compared with the prototypical antagonist 2-methyl-6-(phenylethynyl)-pyridine. The Journal of pharmacology and experimental therapeutics, 330(3):834-43.

 PubMed


The effects of tail biopsy for genotyping on behavioral responses to nociceptive stimuli.

Morales M.E.P., Gereau IV R.W. (2009) The effects of tail biopsy for genotyping on behavioral responses to nociceptive stimuli. PloS one, 4(7):e6457.

 PubMed


The c-kit signaling pathway is involved in the development of persistent pain.

Sun Y.-G., Gracias N.G., Drobish J.K., Vasko M.R., Gereau R.W., Chen Z.-F. (2009) The c-kit signaling pathway is involved in the development of persistent pain. Pain, 144(1-2):178-86.

 PubMed


Epigenetic modulation of mGlu2 receptors by histone deacetylase inhibitors in the treatment of inflammatory pain.

Chiechio S., Zammataro M., Morales M.E., Busceti C.L., Drago F., Gereau IV R.W., Copani A., Nicoletti F. (2009) Epigenetic modulation of mGlu2 receptors by histone deacetylase inhibitors in the treatment of inflammatory pain. Molecular pharmacology, 75(5):1014-20.

 PubMed


MAP kinase and pain.

Ji R.-R., Gereau IV R.W., Malcangio M., Strichartz G.R. (2009) MAP kinase and pain. Brain research reviews, 60(1):135-48.

 PubMed


Metabotropic receptors for glutamate and GABA in pain.

Goudet C., Magnaghi V., Landry M., Nagy F., Gereau IV R.W., Pin J.-P. (2009) Metabotropic receptors for glutamate and GABA in pain. Brain research reviews, 60(1):43-56.

 PubMed