Recent developments in structure-activity relationships for steroid modulators of GABA(A) receptors.

Covey D.F., Evers A.S., Mennerick S., Zorumski C.F., Purdy R.H. (2001) Recent developments in structure-activity relationships for steroid modulators of GABA(A) receptors. Brain research. Brain research reviews, 37(1-3):91-7.

 PubMed


Effects on gamma-aminobutyric acid (GABA)(A) receptors of a neuroactive steroid that negatively modulates glutamate neurotransmission and augments GABA neurotransmission.

Mennerick S., Zeng C.-M., Benz A., Shen W., Izumi Y., Evers A.S., Covey D.F., Zorumski C.F. (2001) Effects on gamma-aminobutyric acid (GABA)(A) receptors of a neuroactive steroid that negatively modulates glutamate neurotransmission and augments GABA neurotransmission. Molecular pharmacology, 60(4):732-41.

 PubMed