Neurosteroid analogues. 8. Structure-activity studies of N-acylated 17a-aza-D-homosteroid analogues of the anesthetic steroids (3alpha, 5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one.

Covey D.F., Han M., Sampath Kumar A., De la Cruz M.A.M., Meadows E.S., Hu Y., Tonnies A., Nathan D., Coleman M., Benz A., Evers A.S., Zorumski C.F., Mennerick S. (2000) Neurosteroid analogues. 8. Structure-activity studies of N-acylated 17a-aza-D-homosteroid analogues of the anesthetic steroids (3alpha, 5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one. Journal of medicinal chemistry, 43(17):3201-4.

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Steroid inhibition of rat neuronal nicotinic alpha4beta2 receptors expressed in HEK 293 cells.

Paradiso K., Sabey K., Evers A.S., Zorumski C.F., Covey D.F., Steinbach J.H. (2000) Steroid inhibition of rat neuronal nicotinic alpha4beta2 receptors expressed in HEK 293 cells. Molecular pharmacology, 58(2):341-51.

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Enantioselectivity of pregnanolone-induced gamma-aminobutyric acid(A) receptor modulation and anesthesia.

Covey D.F., Nathan D., Kalkbrenner M., Nilsson K.R., Hu Y., Zorumski C.F., Evers A.S. (2000) Enantioselectivity of pregnanolone-induced gamma-aminobutyric acid(A) receptor modulation and anesthesia. The Journal of pharmacology and experimental therapeutics, 293(3):1009-16.

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