In Reply.

Avidan MS, Evers AS (2016) In Reply. Anesthesiology, 125(2):428-9.

 PubMed


Activation and modulation of recombinant glycine and GABAA receptors by 4-halogenated analogues of propofol.

Germann AL, Shin DJ, Manion BD, Edge CJ, Smith EH, Franks NP, Evers AS, Akk G (2016) Activation and modulation of recombinant glycine and GABAA receptors by 4-halogenated analogues of propofol. British journal of pharmacology, 173(21):3110-3120.

 PubMed


The GAS trial.

Orser BA, Evers AS, Suresh S, Hertz S (2016) The GAS trial. Lancet (London, England), 387(10028):1613-4.

 PubMed


Multiple Non-Equivalent Interfaces Mediate Direct Activation of GABAA Receptors by Propofol.

Eaton MM, Germann AL, Arora R, Cao LQ, Gao X, Shin DJ, Wu A, Chiara DC, Cohen JB, Steinbach JH (2016) Multiple Non-Equivalent Interfaces Mediate Direct Activation of GABAA Receptors by Propofol. Current neuropharmacology, 14(7):772-780.

 PubMed


The Fallacy of Persistent Postoperative Cognitive Decline.

Avidan MS, Evers AS (2016) The Fallacy of Persistent Postoperative Cognitive Decline. Anesthesiology, 124(2):255-8.

 PubMed


Mutational Analysis of the Putative High-Affinity Propofol Binding Site in Human β3 Homomeric GABAA Receptors.

Eaton MM, Cao LQ, Chen Z, Franks NP, Evers AS, Akk G (2015) Mutational Analysis of the Putative High-Affinity Propofol Binding Site in Human β3 Homomeric GABAA Receptors. Molecular pharmacology, 88(4):736-45.

 PubMed


Anesthetic neurotoxicity--clinical implications of animal models.

Rappaport BA, Suresh S, Hertz S, Evers AS, Orser BA (2015) Anesthetic neurotoxicity--clinical implications of animal models. The New England journal of medicine, 372(9):796-7.

 PubMed


The neurosteroid 5β-pregnan-3α-ol-20-one enhances actions of etomidate as a positive allosteric modulator of α1β2γ2L GABAA receptors.

Li P, Bracamontes JR, Manion BD, Mennerick S, Steinbach JH, Evers AS, Akk G (2014) The neurosteroid 5β-pregnan-3α-ol-20-one enhances actions of etomidate as a positive allosteric modulator of α1β2γ2L GABAA receptors. British journal of pharmacology, 171(23):5446-57.

 PubMed


11-trifluoromethyl-phenyldiazirinyl neurosteroid analogues: potent general anesthetics and photolabeling reagents for GABAA receptors.

Chen ZW, Wang C, Krishnan K, Manion BD, Hastings R, Bracamontes J, Taylor A, Eaton MM, Zorumski CF, Steinbach JH, Akk G, Mennerick S, Covey DF, Evers AS (2014) 11-trifluoromethyl-phenyldiazirinyl neurosteroid analogues: potent general anesthetics and photolabeling reagents for GABAA receptors. Psychopharmacology, 231(17):3479-91.

 PubMed


Surgical safety checklists in ontario, Canada.

Avidan MS, Evers AS (2014) Surgical safety checklists in ontario, Canada. The New England journal of medicine, 370(24):2350-1.

 PubMed


Neurosteroid analogues. 18. Structure-activity studies of ent-steroid potentiators of γ-aminobutyric acid type A receptors and comparison of their activities with those of alphaxalone and allopregnanolone.

Qian M, Krishnan K, Kudova E, Li P, Manion BD, Taylor A, Elias G, Akk G, Evers AS, Zorumski CF (2014) Neurosteroid analogues. 18. Structure-activity studies of ent-steroid potentiators of γ-aminobutyric acid type A receptors and comparison of their activities with those of alphaxalone and allopregnanolone. Journal of medicinal chemistry, 57(1):171-90.

 PubMed


A propofol binding site on mammalian GABAA receptors identified by photolabeling.

Yip GM, Chen ZW, Edge CJ, Smith EH, Dickinson R, Hohenester E, Townsend RR, Fuchs K, Sieghart W, Evers AS (2013) A propofol binding site on mammalian GABAA receptors identified by photolabeling. Nature chemical biology, 9(11):715-20.

 PubMed


Increased Risk of Intraoperative Awareness in Patients with a History of Awareness.

Aranake A, Gradwohl S, Ben-Abdallah A, Lin N, Shanks A, Helsten DL, Glick DB, Jacobsohn E, Villafranca AJ, Evers AS (2013) Increased Risk of Intraoperative Awareness in Patients with a History of Awareness. Anesthesiology, ():.

 PubMed


Neurosteroid analog photolabeling of a site in the third transmembrane domain of the β3 subunit of the GABA(A) receptor.

Chen ZW, Manion B, Townsend RR, Reichert DE, Covey DF, Steinbach JH, Sieghart W, Fuchs K, Evers AS (2012) Neurosteroid analog photolabeling of a site in the third transmembrane domain of the β3 subunit of the GABA(A) receptor. Molecular pharmacology, 82(3):408-19.

 PubMed


Characteristics of concatemeric GABA(A) receptors containing α4/δ subunits expressed in Xenopus oocytes.

Shu H.-J., Bracamontes J., Taylor A., Wu K., Eaton M.M., Akk G., Manion B., Evers A.S., Krishnan K., Covey D.F., Zorumski C.F., Steinbach J.H., Mennerick S. (2012) Characteristics of concatemeric GABA(A) receptors containing α4/δ subunits expressed in Xenopus oocytes. British journal of pharmacology, 165(7):2228-43.

 PubMed


Perspective: Hospital support for anesthesiology departments: aligning incentives and improving productivity.

Hill L.L., Evers A.S. (2012) Perspective: Hospital support for anesthesiology departments: aligning incentives and improving productivity. Academic medicine : journal of the Association of American Medical Colleges, 87(3):348-55.

 PubMed


Neurosteroid analogues. 17. Inverted binding orientations of androsterone enantiomers at the steroid potentiation site on γ-aminobutyric acid type A receptors.

Krishnan K., Manion B.D., Taylor A., Bracamontes J., Steinbach J.H., Reichert D.E., Evers A.S., Zorumski C.F., Mennerick S., Covey D.F. (2012) Neurosteroid analogues. 17. Inverted binding orientations of androsterone enantiomers at the steroid potentiation site on γ-aminobutyric acid type A receptors. Journal of medicinal chemistry, 55(3):1334-45.

 PubMed


A neurosteroid analogue photolabeling reagent labels the colchicine-binding site on tubulin: a mass spectrometric analysis.

Chen Z.-W., Chen L.-H., Akentieva N., Lichti C.F., Darbandi R., Hastings R., Covey D.F., Reichert D.E., Townsend R.R., Evers A.S. (2012) A neurosteroid analogue photolabeling reagent labels the colchicine-binding site on tubulin: a mass spectrometric analysis. Electrophoresis, 33(4):666-74.

 PubMed


Ketamine-induced neuroapoptosis in the fetal and neonatal rhesus macaque brain.

Brambrink A.M., Evers A.S., Avidan M.S., Farber N.B., Smith D.J., Martin L.D., Dissen G.A., Creeley C.E., Olney J.W. (2012) Ketamine-induced neuroapoptosis in the fetal and neonatal rhesus macaque brain. Anesthesiology, 116(2):372-84.

 PubMed


Deep amino acid sequencing of native brain GABAA receptors using high-resolution mass spectrometry.

Chen Z.W., Fuchs K., Sieghart W., Townsend R.R., Evers A.S. (2012) Deep amino acid sequencing of native brain GABAA receptors using high-resolution mass spectrometry. Molecular & cellular proteomics : MCP, 11(1):M111.011445.

 PubMed


Relationship between bispectral index values and volatile anesthetic concentrations during the maintenance phase of anesthesia in the B-Unaware trial.

Whitlock E.L., Villafranca A.J., Lin N., Palanca B.J., Jacobsohn E., Finkel K.J., Zhang L., Burnside B.A., Kaiser H.A., Evers A.S., Avidan M.S. (2011) Relationship between bispectral index values and volatile anesthetic concentrations during the maintenance phase of anesthesia in the B-Unaware trial. Anesthesiology, 115(6):1209-18.

 PubMed


Memories and dreams: building an academic department at Washington University in St. Louis.

Evers A.S., Owens W.D. (2011) Memories and dreams: building an academic department at Washington University in St. Louis. Anesthesiology, 115(6):1147-8.

 PubMed


Congratulations from the IARS!

Congratulations from the IARS! Anesthesiology, 115(4):679-80.

 PubMed


Prevention of intraoperative awareness in a high-risk surgical population.

Avidan M.S., Jacobsohn E., Glick D., Burnside B.A., Zhang L., Villafranca A., Karl L., Kamal S., Torres B., O'Connor M., Evers A.S., Gradwohl S., Lin N., Palanca B.J., Mashour G.A. (2011) Prevention of intraoperative awareness in a high-risk surgical population. The New England journal of medicine, 365(7):591-600.

 PubMed


Neurosteroid analogues. 16. A new explanation for the lack of anesthetic effects of δ(16)-alphaxalone and identification of a δ(17(20)) analogue with potent anesthetic activity.

Stastna E., Krishnan K., Manion B.D., Taylor A., Rath N.P., Chen Z.-W., Evers A.S., Zorumski C.F., Mennerick S., Covey D.F. (2011) Neurosteroid analogues. 16. A new explanation for the lack of anesthetic effects of δ(16)-alphaxalone and identification of a δ(17(20)) analogue with potent anesthetic activity. Journal of medicinal chemistry, 54(11):3926-34.

 PubMed


Review of clinical evidence for persistent cognitive decline or incident dementia attributable to surgery or general anesthesia.

Avidan M.S., Evers A.S. (2011) Review of clinical evidence for persistent cognitive decline or incident dementia attributable to surgery or general anesthesia. Journal of Alzheimer's disease : JAD, 24(2):201-16.

 PubMed


Neurosteroid analogues. 15. A comparative study of the anesthetic and GABAergic actions of alphaxalone, Δ16-alphaxalone and their corresponding 17-carbonitrile analogues.

Bandyopadhyaya A.K., Manion B.D., Benz A., Taylor A., Rath N.P., Evers A.S., Zorumski C.F., Mennerick S., Covey D.F. (2010) Neurosteroid analogues. 15. A comparative study of the anesthetic and GABAergic actions of alphaxalone, Δ16-alphaxalone and their corresponding 17-carbonitrile analogues. Bioorganic & medicinal chemistry letters, 20(22):6680-4.

 PubMed


Postoperative cognitive decline: the unsubstantiated phenotype.

Avidan M.S., Xiong C., Evers A.S. (2010) Postoperative cognitive decline: the unsubstantiated phenotype. Anesthesiology, 113(5):1246-8; author reply 1248-50.

 PubMed


Leadership in postgraduate medical education.

Leadership in postgraduate medical education. Anesthesiology, 113(3):754; author reply 754-5.

 PubMed


A synthetic 18-norsteroid distinguishes between two neuroactive steroid binding sites on GABAA receptors.

Evers A.S., Chen Z.-W., Manion B.D., Han M., Jiang X., Darbandi-Tonkabon R., Kable T., Bracamontes J., Zorumski C.F., Mennerick S., Steinbach J.H., Covey D.F. (2010) A synthetic 18-norsteroid distinguishes between two neuroactive steroid binding sites on GABAA receptors. The Journal of pharmacology and experimental therapeutics, 333(2):404-13.

 PubMed


Isoflurane-induced neuroapoptosis in the neonatal rhesus macaque brain.

Brambrink A.M., Evers A.S., Avidan M.S., Farber N.B., Smith D.J., Zhang X., Dissen G.A., Creeley C.E., Olney J.W. (2010) Isoflurane-induced neuroapoptosis in the neonatal rhesus macaque brain. Anesthesiology, 112(4):834-41.

 PubMed


Kinetic and structural determinants for GABA-A receptor potentiation by neuroactive steroids.

Akk G, Covey DF, Evers AS, Mennerick S, Zorumski CF, Steinbach JH Kinetic and structural determinants for GABA-A receptor potentiation by neuroactive steroids. Current neuropharmacology, 8(1):18-25.

 PubMed


The influence of the membrane on neurosteroid actions at GABA(A) receptors.

Akk G., Covey D.F., Evers A.S., Steinbach J.H., Zorumski C.F., Mennerick S. (2009) The influence of the membrane on neurosteroid actions at GABA(A) receptors. Psychoneuroendocrinology, 34 Suppl 1():S59-66.

 PubMed


Long-term cognitive decline in older subjects was not attributable to noncardiac surgery or major illness.

Avidan M.S., Searleman A.C., Storandt M., Barnett K., Vannucci A., Saager L., Xiong C., Grant E.A., Kaiser D., Morris J.C., Evers A.S. (2009) Long-term cognitive decline in older subjects was not attributable to noncardiac surgery or major illness. Anesthesiology, 111(5):964-70.

 PubMed


Photodynamic effects of steroid-conjugated fluorophores on GABAA receptors.

Shu H.-J., Eisenman L.N., Wang C., Bandyopadhyaya A.K., Krishnan K., Taylor A., Benz A.M., Manion B., Evers A.S., Covey D.F., Zorumski C.F., Mennerick S. (2009) Photodynamic effects of steroid-conjugated fluorophores on GABAA receptors. Molecular pharmacology, 76(4):754-65.

 PubMed


Performance of certified registered nurse anesthetists and anesthesiologists in a simulation-based skills assessment.

Performance of certified registered nurse anesthetists and anesthesiologists in a simulation-based skills assessment. Anesthesia and analgesia, 108(1):255-62.

 PubMed


Potential of xenon to induce or to protect against neuroapoptosis in the developing mouse brain.

Cattano D., Williamson P., Fukui K., Avidan M., Evers A.S., Olney J.W., Young C. (2008) Potential of xenon to induce or to protect against neuroapoptosis in the developing mouse brain. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 55(7):429-36.

 PubMed


Anesthesia awareness and the bispectral index.

Avidan M.S., Zhang L., Burnside B.A., Finkel K.J., Searleman A.C., Selvidge J.A., Saager L., Turner M.S., Rao S., Bottros M., Hantler C., Jacobsohn E., Evers A.S. (2008) Anesthesia awareness and the bispectral index. The New England journal of medicine, 358(11):1097-108.

 PubMed


Mechanisms of potentiation of the mammalian GABAA receptor by the marine cembranoid eupalmerin acetate.

Li P., Reichert D.E., Rodriguez A.D., Manion B.D., Evers A.S., Eterovic V.A., Steinbach J.H., Akk G. (2008) Mechanisms of potentiation of the mammalian GABAA receptor by the marine cembranoid eupalmerin acetate. British journal of pharmacology, 153(3):598-608.

 PubMed


Neurosteroid analogues. 12. Potent enhancement of GABA-mediated chloride currents at GABAA receptors by ent-androgens.

Katona B.W., Krishnan K., Cai Z.Y., Manion B.D., Benz A., Taylor A., Evers A.S., Zorumski C.F., Mennerick S., Covey D.F. (2008) Neurosteroid analogues. 12. Potent enhancement of GABA-mediated chloride currents at GABAA receptors by ent-androgens. European journal of medicinal chemistry, 43(1):107-13.

 PubMed


Performance of residents and anesthesiologists in a simulation-based skill assessment.

Murray D.J., Boulet J.R., Avidan M., Kras J.F., Henrichs B., Woodhouse J., Evers A.S. (2007) Performance of residents and anesthesiologists in a simulation-based skill assessment. Anesthesiology, 107(5):705-13.

 PubMed


Mechanisms of neurosteroid interactions with GABA(A) receptors.

Akk G., Covey D.F., Evers A.S., Steinbach J.H., Zorumski C.F., Mennerick S. (2007) Mechanisms of neurosteroid interactions with GABA(A) receptors. Pharmacology & therapeutics, 116(1):35-57.

 PubMed


Identification and characterization of cholest-4-en-3-one, oxime (TRO19622), a novel drug candidate for amyotrophic lateral sclerosis.

Bordet T., Buisson B., Michaud M., Drouot C., Galea P., Delaage P., Akentieva N.P., Evers A.S., Covey D.F., Ostuni M.A., Lacapere J.-J., Massaad C., Schumacher M., Steidl E.-M., Maux D., Delaage M., Henderson C.E., Pruss R.M. (2007) Identification and characterization of cholest-4-en-3-one, oxime (TRO19622), a novel drug candidate for amyotrophic lateral sclerosis. The Journal of pharmacology and experimental therapeutics, 322(2):709-20.

 PubMed


Can we get there if we don't know where we're going?

Evers A.S., Miller R.D. (2007) Can we get there if we don't know where we're going? Anesthesiology, 106(4):651-2.

 PubMed


Anticonvulsant and anesthetic effects of a fluorescent neurosteroid analog activated by visible light.

Eisenman L.N., Shu H.-J., Akk G., Wang C., Manion B.D., Kress G.J., Evers A.S., Steinbach J.H., Covey D.F., Zorumski C.F., Mennerick S. (2007) Anticonvulsant and anesthetic effects of a fluorescent neurosteroid analog activated by visible light. Nature neuroscience, 10(4):523-30.

 PubMed


Ethanol modulates the interaction of the endogenous neurosteroid allopregnanolone with the alpha1beta2gamma2L GABAA receptor.

Akk G., Li P., Manion B.D., Evers A.S., Steinbach J.H. (2007) Ethanol modulates the interaction of the endogenous neurosteroid allopregnanolone with the alpha1beta2gamma2L GABAA receptor. Molecular pharmacology, 71(2):461-72.

 PubMed


Neurosteroid analogues. 11. Alternative ring system scaffolds: gamma-aminobutyric acid receptor modulation and anesthetic actions of benz[f]indenes.

Scaglione J.B., Manion B.D., Benz A., Taylor A., DeKoster G.T., Rath N.P., Evers A.S., Zorumski C.F., Mennerick S., Covey D.F. (2006) Neurosteroid analogues. 11. Alternative ring system scaffolds: gamma-aminobutyric acid receptor modulation and anesthetic actions of benz[f]indenes. Journal of medicinal chemistry, 49(15):4595-605.

 PubMed


Intrapatient reproducibility of the BISxp monitor.

Intrapatient reproducibility of the BISxp monitor. Anesthesiology, 104(2):242-8.

 PubMed


Neurosteroid analogues. 10. The effect of methyl group substitution at the C-6 and C-7 positions on the GABA modulatory and anesthetic actions of (3alpha,5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one.

Zeng C.-M., Manion B.D., Benz A., Evers A.S., Zorumski C.F., Mennerick S., Covey D.F. (2005) Neurosteroid analogues. 10. The effect of methyl group substitution at the C-6 and C-7 positions on the GABA modulatory and anesthetic actions of (3alpha,5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one. Journal of medicinal chemistry, 48(8):3051-9.

 PubMed


Selective antagonism of 5alpha-reduced neurosteroid effects at GABA(A) receptors.

Selective antagonism of 5alpha-reduced neurosteroid effects at GABA(A) receptors. Molecular pharmacology, 65(5):1191-7.

 PubMed


Isoflurane inhibits transmitter release and the presynaptic action potential.

Wu X.-S., Sun J.-Y., Evers A.S., Crowder M., Wu L.-G. (2004) Isoflurane inhibits transmitter release and the presynaptic action potential. Anesthesiology, 100(3):663-70.

 PubMed


Neuroactive steroid interactions with voltage-dependent anion channels: lack of relationship to GABA(A) receptor modulation and anesthesia.

Darbandi-Tonkabon R., Manion B.D., Hastings W.R., Craigen W.J., Akk G., Bracamontes J.R., He Y., Sheiko T.V., Steinbach J.H., Mennerick S.J., Covey D.F., Evers A.S. (2004) Neuroactive steroid interactions with voltage-dependent anion channels: lack of relationship to GABA(A) receptor modulation and anesthesia. The Journal of pharmacology and experimental therapeutics, 308(2):502-11.

 PubMed


Neurosteroid analogues. 9. Conformationally constrained pregnanes: structure-activity studies of 13,24-cyclo-18,21-dinorcholane analogues of the GABA modulatory and anesthetic steroids (3alpha,5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one.

Jiang X., Manion B.D., Benz A., Rath N.P., Evers A.S., Zorumski C.F., Mennerick S., Covey D.F. (2003) Neurosteroid analogues. 9. Conformationally constrained pregnanes: structure-activity studies of 13,24-cyclo-18,21-dinorcholane analogues of the GABA modulatory and anesthetic steroids (3alpha,5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one. Journal of medicinal chemistry, 46(25):5334-48.

 PubMed


Mervyn Maze, M.B., Ch.B., F.R.C.P.: recipient of the 2003 Excellence in Research Award.

Evers A.S. (2003) Mervyn Maze, M.B., Ch.B., F.R.C.P.: recipient of the 2003 Excellence in Research Award. Anesthesiology, 99(4):777-8.

 PubMed


Photoaffinity labeling with a neuroactive steroid analogue. 6-azi-pregnanolone labels voltage-dependent anion channel-1 in rat brain.

Darbandi-Tonkabon R., Hastings W.R., Zeng C.-M., Akk G., Manion B.D., Bracamontes J.R., Steinbach J.H., Mennerick S.J., Covey D.F., Evers A.S. (2003) Photoaffinity labeling with a neuroactive steroid analogue. 6-azi-pregnanolone labels voltage-dependent anion channel-1 in rat brain. The Journal of biological chemistry, 278(15):13196-206.

 PubMed


Recent developments in structure-activity relationships for steroid modulators of GABA(A) receptors.

Covey D.F., Evers A.S., Mennerick S., Zorumski C.F., Purdy R.H. (2001) Recent developments in structure-activity relationships for steroid modulators of GABA(A) receptors. Brain research. Brain research reviews, 37(1-3):91-7.

 PubMed


Effects on gamma-aminobutyric acid (GABA)(A) receptors of a neuroactive steroid that negatively modulates glutamate neurotransmission and augments GABA neurotransmission.

Mennerick S., Zeng C.-M., Benz A., Shen W., Izumi Y., Evers A.S., Covey D.F., Zorumski C.F. (2001) Effects on gamma-aminobutyric acid (GABA)(A) receptors of a neuroactive steroid that negatively modulates glutamate neurotransmission and augments GABA neurotransmission. Molecular pharmacology, 60(4):732-41.

 PubMed


Neurosteroid analogues. 8. Structure-activity studies of N-acylated 17a-aza-D-homosteroid analogues of the anesthetic steroids (3alpha, 5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one.

Covey D.F., Han M., Sampath Kumar A., De la Cruz M.A.M., Meadows E.S., Hu Y., Tonnies A., Nathan D., Coleman M., Benz A., Evers A.S., Zorumski C.F., Mennerick S. (2000) Neurosteroid analogues. 8. Structure-activity studies of N-acylated 17a-aza-D-homosteroid analogues of the anesthetic steroids (3alpha, 5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one. Journal of medicinal chemistry, 43(17):3201-4.

 PubMed


Steroid inhibition of rat neuronal nicotinic alpha4beta2 receptors expressed in HEK 293 cells.

Paradiso K., Sabey K., Evers A.S., Zorumski C.F., Covey D.F., Steinbach J.H. (2000) Steroid inhibition of rat neuronal nicotinic alpha4beta2 receptors expressed in HEK 293 cells. Molecular pharmacology, 58(2):341-51.

 PubMed


Enantioselectivity of pregnanolone-induced gamma-aminobutyric acid(A) receptor modulation and anesthesia.

Covey D.F., Nathan D., Kalkbrenner M., Nilsson K.R., Hu Y., Zorumski C.F., Evers A.S. (2000) Enantioselectivity of pregnanolone-induced gamma-aminobutyric acid(A) receptor modulation and anesthesia. The Journal of pharmacology and experimental therapeutics, 293(3):1009-16.

 PubMed


Double-edged swords: volatile anesthetics both enhance and inhibit ligand-gated ion channels.

Evers A.S., Steinbach J.H. (1999) Double-edged swords: volatile anesthetics both enhance and inhibit ligand-gated ion channels. Anesthesiology, 90(1):1-3.

 PubMed


Postanesthesia care unit length of stay: quantifying and assessing dependent factors.

Waddle J.P., Evers A.S., Piccirillo J.F. (1998) Postanesthesia care unit length of stay: quantifying and assessing dependent factors. Anesthesia and analgesia, 87(3):628-33.

 PubMed


Supersensitive sites in the central nervous system. Anesthetics block brain nicotinic receptors.

Evers A.S., Steinbach J.H. (1997) Supersensitive sites in the central nervous system. Anesthetics block brain nicotinic receptors. Anesthesiology, 86(4):760-2.

 PubMed


Enantioselectivity of steroid-induced gamma-aminobutyric acidA receptor modulation and anesthesia.

Wittmer L.L., Hu Y., Kalkbrenner M., Evers A.S., Zorumski C.F., Covey D.F. (1996) Enantioselectivity of steroid-induced gamma-aminobutyric acidA receptor modulation and anesthesia. Molecular pharmacology, 50(6):1581-6.

 PubMed


Volatile anesthetic-induced efflux of calcium from IP3-gated stores in clonal (GH3) pituitary cells.

Hossain M.D., Evers A.S. (1994) Volatile anesthetic-induced efflux of calcium from IP3-gated stores in clonal (GH3) pituitary cells. Anesthesiology, 80(6):1379-89; discussion 27A-28A.

 PubMed


Volatile anesthetic effects on inositol trisphosphate-gated intracellular calcium stores in GH3 cells.

Volatile anesthetic effects on inositol trisphosphate-gated intracellular calcium stores in GH3 cells. Advances in pharmacology (San Diego, Calif.), 31():343-50.

 PubMed


Volatile anesthetics compete for common binding sites on bovine serum albumin: a 19F-NMR study.

Dubois B.W., Cherian S.F., Evers A.S. (1993) Volatile anesthetics compete for common binding sites on bovine serum albumin: a 19F-NMR study. Proceedings of the National Academy of Sciences of the United States of America, 90(14):6478-82.

 PubMed


Direct observation of a fluorinated anticonvulsant in brain tissue using 19F-NMR techniques.

Canney D.J., Covey D.F., Evers A.S. (1993) Direct observation of a fluorinated anticonvulsant in brain tissue using 19F-NMR techniques. Biochemical pharmacology, 45(4):949-59.

 PubMed


19F-NMR spin-spin relaxation (T2) method for characterizing volatile anesthetic binding to proteins. Analysis of isoflurane binding to serum albumin.

Dubois B.W., Evers A.S. (1992) 19F-NMR spin-spin relaxation (T2) method for characterizing volatile anesthetic binding to proteins. Analysis of isoflurane binding to serum albumin. Biochemistry, 31(31):7069-76.

 PubMed


The action of halothane on stimulus-secretion coupling in clonal (GH3) pituitary cells.

Stern R.C., Herrington J., Lingle C.J., Evers A.S. (1991) The action of halothane on stimulus-secretion coupling in clonal (GH3) pituitary cells. The Journal of neuroscience : the official journal of the Society for Neuroscience, 11(7):2217-25.

 PubMed


Halothane inhibits two components of calcium current in clonal (GH3) pituitary cells.

Herrington J., Stern R.C., Evers A.S., Lingle C.J. (1991) Halothane inhibits two components of calcium current in clonal (GH3) pituitary cells. The Journal of neuroscience : the official journal of the Society for Neuroscience, 11(7):2226-40.

 PubMed


19F-nuclear magnetic resonance spectroscopy. Its use in defining molecular sites of anesthetic action.

Evers A.S., Dubois B.W. (1991) 19F-nuclear magnetic resonance spectroscopy. Its use in defining molecular sites of anesthetic action. Annals of the New York Academy of Sciences, 625():725-32.

 PubMed


The action of halothane on stimulus-secretion coupling in clonal (GH3) pituitary cells.

Stern R.C., Evers A.S. (1991) The action of halothane on stimulus-secretion coupling in clonal (GH3) pituitary cells. Annals of the New York Academy of Sciences, 625():293-5.

 PubMed


Elimination kinetics of sevoflurane and halothane from blood, brain, and adipose tissue in the rat.

Stern R.C., Towler S.C., White P.F., Evers A.S. (1990) Elimination kinetics of sevoflurane and halothane from blood, brain, and adipose tissue in the rat. Anesthesia and analgesia, 71(6):658-64.

 PubMed


Isoflurane uptake and elimination are delayed by absorption of anesthetic by the Scimed membrane oxygenator.

Stern R.C., Weiss C.I., Steinbach J.H., Evers A.S. (1989) Isoflurane uptake and elimination are delayed by absorption of anesthetic by the Scimed membrane oxygenator. Anesthesia and analgesia, 69(5):657-62.

 PubMed


Correlation between the anaesthetic effect of halothane and saturable binding in brain.

Evers A.S., Berkowitz B.A., D'Avignon D.A. (1989) Correlation between the anaesthetic effect of halothane and saturable binding in brain. Nature, 341(6244):766.

 PubMed


fMet-Leu-Phe receptor expression by an interstitial cell in rabbit right atrium following left ventricular myocardial infarction.

Dunkel C.G., Saffitz J.E., Evers A.S. (1989) fMet-Leu-Phe receptor expression by an interstitial cell in rabbit right atrium following left ventricular myocardial infarction. Circulation research, 65(1):215-23.

 PubMed


Enhanced inositol trisphosphate response to alpha 1-adrenergic stimulation in cardiac myocytes exposed to hypoxia.

Heathers G.P., Evers A.S., Corr P.B. (1989) Enhanced inositol trisphosphate response to alpha 1-adrenergic stimulation in cardiac myocytes exposed to hypoxia. The Journal of clinical investigation, 83(4):1409-13.

 PubMed


Anion exchange chromatographic separation of inositol phosphates and their quantification by gas chromatography.

Heathers G.P., Juehne T., Rubin L.J., Corr P.B., Evers A.S. (1989) Anion exchange chromatographic separation of inositol phosphates and their quantification by gas chromatography. Analytical biochemistry, 176(1):109-16.

 PubMed


Anesthesia and chemical second messenger generation in the adrenergic nervous system.

Towler S.C., Evers A.S. (1989) Anesthesia and chemical second messenger generation in the adrenergic nervous system. International anesthesiology clinics, 27(4):234-7.

 PubMed


Role of invading leukocytes in enhanced atrial eicosanoid production following rabbit left ventricular myocardial infarction.

Freed M.S., Needleman P., Dunkel C.G., Saffitz J.E., Evers A.S. (1989) Role of invading leukocytes in enhanced atrial eicosanoid production following rabbit left ventricular myocardial infarction. The Journal of clinical investigation, 83(1):205-12.

 PubMed


Altered phosphoinositide fatty acid composition, mass and metabolism in brain essential fatty acid deficiency.

Haycock J.C., Evers A.S. (1988) Altered phosphoinositide fatty acid composition, mass and metabolism in brain essential fatty acid deficiency. Biochimica et biophysica acta, 960(1):54-60.

 PubMed


The potency of fluorinated ether anesthetics correlates with their 19F spin-spin relaxation times in brain tissue.

Evers A.S., Haycock J.C., d'Avignon D.A. (1988) The potency of fluorinated ether anesthetics correlates with their 19F spin-spin relaxation times in brain tissue. Biochemical and biophysical research communications, 151(3):1039-45.

 PubMed


Effect of endogenously produced leukotrienes and thromboxane on renal vascular resistance in rabbit hydronephrosis.

Albrightson C.R., Evers A.S., Griffin A.C., Needleman P. (1987) Effect of endogenously produced leukotrienes and thromboxane on renal vascular resistance in rabbit hydronephrosis. Circulation research, 61(4):514-22.

 PubMed


Correlation between the anaesthetic effect of halothane and saturable binding in brain.

Evers A.S., Berkowitz B.A., D'Avignon D.A. (1987) Correlation between the anaesthetic effect of halothane and saturable binding in brain. Nature, 328(6126):157-60.

 PubMed


Exaggerated atrial arachidonate metabolism in rabbit left ventricular myocardial infarction.

Evers A.S., Dunkel C.G., Saffitz J.E., Needleman P. (1987) Exaggerated atrial arachidonate metabolism in rabbit left ventricular myocardial infarction. The Journal of clinical investigation, 79(1):155-62.

 PubMed


Essential fatty acid deficiency: a new look at an old problem.

Lefkowith J.B., Evers A.S., Elliott W.J., Needleman P. (1986) Essential fatty acid deficiency: a new look at an old problem. Prostaglandins, leukotrienes, and medicine, 23(2-3):123-7.

 PubMed


Manipulation of rat brain fatty acid composition alters volatile anesthetic potency.

Evers A.S., Elliott W.J., Lefkowith J.B., Needleman P. (1986) Manipulation of rat brain fatty acid composition alters volatile anesthetic potency. The Journal of clinical investigation, 77(3):1028-33.

 PubMed


Effects of endogenously produced leukotrienes, thromboxane, and prostaglandins on coronary vascular resistance in rabbit myocardial infarction.

Evers A.S., Murphree S., Saffitz J.E. (1985) Effects of endogenously produced leukotrienes, thromboxane, and prostaglandins on coronary vascular resistance in rabbit myocardial infarction. The Journal of clinical investigation, 75(3):992-9.

 PubMed


Successful treatment of accelerated junctional rhythm with propranolol: possible role of sympathetic stimulation in the genesis of this rhythm disturbance.

Breslow M.J., Evers A.S., Lebowitz P. (1985) Successful treatment of accelerated junctional rhythm with propranolol: possible role of sympathetic stimulation in the genesis of this rhythm disturbance. Anesthesiology, 62(2):180-2.

 PubMed