The Actions of Drug Combinations on the GABAA Receptor Manifest as Curvilinear Isoboles of Additivity.

Shin DJ, Germann AL, Steinbach JH, Akk G  (2017) The Actions of Drug Combinations on the GABAA Receptor Manifest as Curvilinear Isoboles of Additivity. Molecular pharmacology, 92(5):556-563.

 PubMed


Determination of the Residues in the Extracellular Domain of the Nicotinic α Subunit Required for the Actions of Physostigmine on Neuronal Nicotinic Receptors.

Jin X, Germann AL, Shin DJ, Akk G, Steinbach JH  (2017) Determination of the Residues in the Extracellular Domain of the Nicotinic α Subunit Required for the Actions of Physostigmine on Neuronal Nicotinic Receptors. Molecular pharmacology, 92(3):318-326.

 PubMed


Nicotine dependence is associated with functional variation in FMO3, an enzyme that metabolizes nicotine in the brain.

Teitelbaum AM, Murphy SE, Akk G, Baker TB, Germann A, von Weymarn LB, Bierut LJ, Goate A, Kharasch ED, Bloom AJ  (2017) Nicotine dependence is associated with functional variation in FMO3, an enzyme that metabolizes nicotine in the brain. The pharmacogenomics journal, ():.

 PubMed


The E Loop of the Transmitter Binding Site Is a Key Determinant of the Modulatory Effects of Physostigmine on Neuronal Nicotinic α4β2 Receptors.

Jin X, McCollum MM, Germann AL, Akk G, Steinbach JH (2017) The E Loop of the Transmitter Binding Site Is a Key Determinant of the Modulatory Effects of Physostigmine on Neuronal Nicotinic α4β2 Receptors. Molecular pharmacology, 91(2):100-109.

 PubMed