A neurosteroid potentiation site can be moved among GABAA receptor subunits.

Bracamontes JR, Li P, Akk G, Steinbach JH (2012) A neurosteroid potentiation site can be moved among GABAA receptor subunits. The Journal of physiology, 590(Pt 22):5739-47.

 PubMed


Impact of human D398N single nucleotide polymorphism on intracellular calcium response mediated by α3β4α5 nicotinic acetylcholine receptors.

Tammimäki A, Herder P, Li P, Esch C, Laughlin JR, Akk G, Stitzel JA. (2012) Impact of human D398N single nucleotide polymorphism on intracellular calcium response mediated by α3β4α5 nicotinic acetylcholine receptors. Neuropharmacology, 63(6):1002-11.

 PubMed


Neurosteroid analog photolabeling of a site in the third transmembrane domain of the β3 subunit of the GABA(A) receptor.

Chen ZW, Manion B, Townsend RR, Reichert DE, Covey DF, Steinbach JH, Sieghart W, Fuchs K, Evers AS (2012) Neurosteroid analog photolabeling of a site in the third transmembrane domain of the β3 subunit of the GABA(A) receptor. Molecular pharmacology, 82(3):408-19.

 PubMed


Agonist-specific conformational changes in the α1-γ2 subunit interface of the GABA A receptor.

Eaton MM, Lim YB, Bracamontes J, Steinbach JH, Akk G (2012) Agonist-specific conformational changes in the α1-γ2 subunit interface of the GABA A receptor. Molecular pharmacology, 82(2):255-63.

 PubMed


Characteristics of concatemeric GABA(A) receptors containing α4/δ subunits expressed in Xenopus oocytes.

Shu H.-J., Bracamontes J., Taylor A., Wu K., Eaton M.M., Akk G., Manion B., Evers A.S., Krishnan K., Covey D.F., Zorumski C.F., Steinbach J.H., Mennerick S. (2012) Characteristics of concatemeric GABA(A) receptors containing α4/δ subunits expressed in Xenopus oocytes. British journal of pharmacology, 165(7):2228-43.

 PubMed


Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence.

Haller G, Druley T, Vallania FL, Mitra RD, Li P, Akk G, Steinbach JH, Breslau N, Johnson E, Hatsukami D, Stitzel J, Bierut LJ, Goate AM Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence. Human molecular genetics, 21(3):647-55.

 PubMed